Hulk Hogan Thinks His Daughter Brooke Hogan Is Sexy! (Photos)
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Source: http://stupidcelebrities.net/2013/01/hulk-hogan-thinks-his-daughter-brooke-is-sexy-photos/
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Study shows potential of differentiated iPS cells in cell therapy without immune rejection
Monday, January 28, 2013A new study from Boston University School of Medicine (BUSM) shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The study, published online in Cell Stem Cell, demonstrates the potential of utilizing iPS cells to develop cell types that could offer treatment for a wide range of conditions, including diabetes, liver and lung diseases, without the barrier of immune rejection.
Ashleigh Boyd, DPhil, and Neil Rodrigues, DPhil, the study's senior authors, are assistant professors of dermatology at BUSM and researchers at the Center for Regenerative Medicine (CReM) at Boston University and Boston Medical Center (BMC). They also are lead investigators at the National Institutes of Health's Center of Biomedical Research Excellence (COBRE) at Roger Williams Medical Center, a clinical and research affiliate of BUSM.
iPS cells can be developed from adult cell types, such as skin or blood, by returning them to a stem cell state using genetic manipulation. iPS cells are capable of maturing (differentiating) into all the specific cell types in the body, making them a powerful tool for biological research and a source of tissues for transplantation based therapies. Given that iPS cells can be made in a patient-specific manner, there should be great potential for them to be transplanted back into the same patient without rejection. Yet a study published in Nature in 2011 demonstrated that iPS cells transplanted in the stem cell state were rejected in genetically identical recipients.
"The Nature study provocatively suggested that tissues derived from patient-specific iPS cells may be immunogenic after transplantation. However, it never directly assessed the immunogenicity of the therapeutically relevant cell types that could be utilized in regenerative medicine and transplantation," said Rodrigues.
The BUSM researchers evaluated this matter by taking adult cells from an experimental model and deriving iPS cells from them. They then differentiated the iPS cells into three cell types: neuronal (nerve); hepatocytes (liver); and endothelial (blood vessel lining) cells. These three cell types represent each of the three germ layers present during embryonic development ? mesoderm, ectoderm and endoderm. Cells from these layers differentiate and ultimately develop into the body's tissue and organ systems. Using experiments to mirror the potential clinical use of patient-specific iPS cells in cell therapy, the team transplanted each of the differentiated cells into a genetically identical experimental model and found no signs of an elevated immune response or indications of rejection.
The study results suggest that using patient-specific iPS cells should overcome issues of immune rejection in transplantation, which will be a significant problem for potential embryonic stem cell-derived therapies. Immune rejection in transplantation is treated clinically by immunosuppressive drugs but they can have serious side-effects, including the risk of developing cancer.
"If the use of immunosuppressive drugs can be avoided, as may be the case for patient-specific iPS cell based therapies, it would be preferable. Our results are very promising and future work should be directed at assessing whether tissues derived from human iPS cells will similarly lack immunogenicity," said Boyd.
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Boston University Medical Center: http://www.bmc.org
Thanks to Boston University Medical Center for this article.
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KABUL/KANDAHAR, Afghanistan (Reuters) - Charred bodies lie scattered against blood-stained walls and debris covers the ground. For Afghanistan, the only unusual thing in this gruesome scene is that the blood is red paint - and part of an art installation.
It's a work by 23-year-old Afghan artist Malina Suliman, who risks her life, sometimes working by flashlight after dark, to create art in southern Kandahar province, the birthplace of the Taliban and still one of the country's most dangerous areas.
Her pieces, which range from conceptual art to paintings and sculpture, are bold representations of the problems facing her generation and have drawn praise from top officials in Kandahar, making her exceptional in a place where women face even greater restrictions than in other parts of the country.
"Many people had never seen an art installation... Some were offended and others were hurt because they'd experienced it before," Suliman said of "War and Chaos," which was in an exhibit last year and depicts the aftermath of a suicide bombing, an all too common event in Kandahar.
Her haunting, powerful pieces earned her an invitation last year to President Hamid Karzai's palace in Kabul, where she showed her art to the Afghan leader, who is also from Kandahar.
Suliman's artwork is now making waves in the Afghan capital of Kabul, where she lived after fleeing the violence of her native province as a child. In December, she had two exhibits there, a highlight of which was a sculpture of a woman in baggy clothing with a noose tied around her neck.
An exhibit in Kandahar, where the Taliban and tribal elders dominate public opinion, was the first there in three decades. She drew a mostly male crowd of around 100, including Kandahar governor Tooryalai Wesa and some of Karzai's relatives.
"I was taken aback by her work. I had only seen great art abroad, but never here," Wesa later told Reuters, recalling the exhibit, which featured a painting of a foetus in the womb suspended from a tree and being pulled in different ways. "I hope it persuades more women to do the same."
Suliman said this piece, called "Today's Life", reflected the frustrations of her generation.
"Before a child is born, the parents are already thinking that a son can support them and a daughter can be married off to a wealthy suitor. They don't stop to think what the child may want," she said.
SLOW PROGRESS FOR ART
Thirty years of war and conflict, starting with the Soviet invasion of 1979, effectively shelved Afghanistan's art scene. The austere 1996-2001 rule of the Taliban then banned most art outright, declaring it un-Islamic.
Since the Islamist group was toppled by U.S.-backed Afghan forces almost twelve years ago, large Afghan cities have resurrected something of an art movement, but progress is slow.
Herat city, in the country's west, now has art studios for rent, while Mazar-e-Sharif in the north has an artist collective and a lively graffiti scene.
Suliman, who is self-confident and energetic with almond-shaped eyes, joined the Kandahar Fine Art Association, a relatively new, all-male group whose goal is to support and exhibit local art, one year ago.
The small collective of 10 artists caught the eye of the Ministry of Information and Culture, which funded and last year opened Kandahar's first art gallery, where Suliman has exhibited. Since she joined the collective, several more Kandahar-based female artists have come on board.
But the stakes remain high.
"One of our biggest fears is that people will mistake us for creating art for foreigners or working with NGOs. People who work with NGOs get shot without question in Kandahar," she said.
Despite her success, Suliman has received threatening phonecalls warning her against attending her own exhibits, and the Taliban have spoken out against her.
Even creating her art must take place away from public view. She often waits until after dusk, working with a dim flashlight.
Suliman recalls her first exhibit in Kandahar last year, and how she trembled as she made her way towards the gallery, in fear of it being bombed.
"I was so scared... Whenever there is a gathering of government officials it becomes a target," she said.
But one of Suliman's greatest challenges lies at home.
"The night of my first exhibit my family told me 'if you go, don't come back'," she said with a wry laugh.
While her sisters and mother now support her ambition and passion, her brothers and property developer father remain fiercely opposed -- attitudes typical for Afghanistan.
She is now looking to expand Kandahar's budding art scene to nearby Helmand, hoping to secure locally-sourced funds for workshops and training.
When asked if she is scared, she mentions her sculpture of the hanged woman and smiles.
"That's what happens to women when they ask for their rights in this country," she says, impudently.
(Reporting by Miriam Arghandiwal, additional reporting by Sarwar Amani, Editing by Amie Ferris-Rotman and Elaine Lies)
Source: http://news.yahoo.com/afghan-female-artist-beats-odds-create-050722988.html
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All you need to do is pull back the glue on the sides of the boxes, unfold, and then you have a plate. You should be able to do the same thing with the containers that have the wire handle too, but you'll have to remove the handle first. It's not exactly the world's most perfect plate, but it should work in a pinch.
So Apparently, We've Been Using Chinese Takeout Boxes All Wrong | Foodbeast
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LONDON (AP) ? Prince Harry's off-duty time in Afghanistan appeared to be full of war movies, board games and elaborate candy trades.
The 28-year-old helicopter pilot and fellow members of his squad swapped Kit Kats and Rice Krispies Squares for American soldiers' M&Ms, according to a British media pool report released Sunday.
Harry himself outlined one of his less-prestigious duties. The third-in-line to the U.K. throne said anyone who lost at Uckers ? a military game similar to Ludo or Parcheesi ? had to then wait on his comrades like a Buckingham Palace butler, ready with a fresh cup of tea whenever anyone rang their bell.
"Whoever loses ... then you have to make brews for everybody all day," Harry told journalists ahead of his return to Britain this week.
He also denied rumors that he was far better at PlayStation than at traditional board games.
"I don't know who told you that," he told reporters. "I lost two days ago, and yesterday, so since you guys have been here I've only lost."
Harry returned to Britain on Wednesday after a 20-week deployment in Afghanistan in which he acknowledged that he had targeted Taliban fighters from the cockpit of his Apache attack helicopter.
Asked in an earlier round of interviews whether he had killed anyone, Harry said: "Yeah, so, lots of people have." That admission disturbed some Britons and led to front-page headlines like the one in The Daily Mail that read: "Harry: I Have Killed."
This latest round of interviews, focusing on Harry's daily life at Britain's Camp Bastion military base in Afghanistan, is not likely to draw the same kind of headlines.
The report mainly carried glimpses of the prince's daily routine, including his favorite foods ? chicken and broccoli ? and his favorite movies ? "Full Metal Jacket," ''Apocalypse Now," and "Platoon."
In an interesting twist for an Apache pilot, "Black Hawk Down," the Ridley Scott film about a helicopter raid gone wrong in Somalia, was among the movies spotted in Harry's communal tent.
Source: http://news.yahoo.com/harrys-afghan-downtime-movies-candy-trades-090928405.html
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